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科学研究    

何伟


教育背景:

2011.09-2016.06 南京工业大学,制药工程,博士

研究工作背景:

2016.07-2018.09 复旦大学,化学系,博士后

2018.10-至今南京工业大学,副教授

科研工作及成果:

(1)主要研究工作:基于微反应技术,开发新型的“微化工+”技术;利用“微化工+”技术进行生物基化学品及材料开发;利用计算模拟技术解析“微化工+”技术在生物基材料开发过程中的过程强化作用。

(2)于国内外核心期刊上发表科研论文20篇,在Chem. Eng. J., Ind. Eng. Chem. Res.等化工领域主流期刊发表SCI收录17篇,其中以第一作者身份发表SCI论文13篇;申请专利30项,已授权中国专利19项,美国专利1项。

(3)2016年获中国石油和化学工业联合会技术发明一等奖,2012年获无锡市科技进步奖二等奖。

(4)作为项目负责人,主持国家自然科学基金青年基金1项,中国博士后科学基金一等资助和特别资助各1项,江苏省研究生科研创新计划1项;并以研究骨干重点参与完成了国家基金委重点项目、国家科技部973计划、863计划等多个国家大型科研项目。

代表性论文:

(1)W. He, G. Zhu, Y. Gao, H. Wu, Z. Fang, K. Guo. Green plasticizers derived from epoxidized soybean oil for poly (vinyl chloride): Continuous synthesis and evaluation in PVC films.Chem. Eng. J., 2020, 380, 122532.一区Top期刊

(2)W. He, Y. Gao, G. Zhu, H. Wu, Z. Fang, K. Guo. Microfluidic synthesis of fatty acid esters: Integration of dynamic combinatorial chemistry and scale effect.Chem. Eng. J., 10.1016/j.cej.2019.122721.一区Top期刊

(3)W. He, Z. Fang, K. Zhang, T. Tu, N. Lv, C. Qiu, K. Guo. A novel micro-flow system under microwave irradiation for continuous synthesis of 1, 4-dihydropyridines in the absence of solvents via Hantzsch reaction.Chem. Eng. J.2018, 331, 161-168. 一区Top期刊

(4) Z. Fang1,W. He1, N. Lv, C. Qiu, X. Li, N. Zhu, L. Wan, K. Guo. An efficient and green pathway for continuous Friedel-Crafts acylation over α-Fe2O3and CaCO3nanoparticles prepared in the microreactors.Chem. Eng. J., 2018, 331, 443-449. 一区Top期刊

(5)W. He, Z. Fang, Q. Tian, W. Shen, K. Guo. Tandem, effective continuous flow process for the epoxidation of cyclohexene.Ind. Eng. Chem. Res., 2016, 55, 1373-1379.二区Top期刊

(6)W. He, Z. Fang, D. Ji, K. Guo*. Expoxidation of Soybean Oil by Continuous Micro-Flow System with Continuous Separation.Org. Process Res. Dev.2013, 12, 1137-1141.

(7)W. He, D. Ji, Z. Fang, K. Zhang, K. Guo. Two-stage continuous flow synthesis of epoxidized FAMEs in the micro-flow system.Chem. Eng. Process., 2015, 39-43.

(8) Z. Fang1,W. He1, X. Li, Z. J. Li, B. N. Chen, P. K. Ouyang, K. Guo. A novel protocol to accelerate dynamic combinatorial chemistry via isolation of ligand-target adducts from dynamic combinatorial libraries: A case study identifying competitive inhibitors of lysozyme.Bioorg. Med. Chem. Lett. 23, 5174-5177, 2013.

(9)W. He, Z. Fang, Z. Yang, D. Ji, K. Chen, K. Guo. Identification of competitive inhibitors for bovine serum albumin from dynamic combinatorial libraries containing a bienzyme system.RSC Adv., 2015, 5, 23224-23228.

(10)W. He, Z. Fang, Z. Yang, D. Ji, K. Guo.Heteropoly Acid-catalyzed Three-component Aza-Diels-Alder Cyclizations in a Continuous Micro-flow System.RSC Adv., 2015, 5, 58798-58803.

(11)W. He, Z. Fang, K. Zhang, X. Li, D. Ji, X. Jiang, C. Qiu, K. Guo. Continuous synthesis of co-dopedTiO2photocatalyst in the micro-flow system and its enhanced visible light catalytic activity in degradation of organic water pollutants using a photocatalysis microreactor.RSC Adv., 2015, 5, 54853-54860.

(12)W. He, Z. Fang, D. Ji, K. Zhang, K. Guo. Optimization of biodiesel production by continuous microflow system with online separation.Monatsh. Chem.2014, 145, 223-227.

(13)W. He, Z. Fang, N. Zhu, D. Ji, Z. Li, K. Guo. Ring-opening polymerization of ε-caprolactone catalyzed by a novel lipase Candida sp. 99-125.Biocatal. biotransfor., 2015, 33(3), 150-155.




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